A rapid detection method for the surface defects of mosaic ceramic tiles

Due to its unique artistic value, mosaic ceramics are widely used in construction-related fields. To meet the artist's demand for high-quality mosaic ceramic to create artistic works, it is necessary to meet the needs for efficient screening of mosaic ceramic tiles. Different from the ordinary large-target ceramics, mosaic ceramics exhibit characteristics of small tile sizes, a variety of colors, large demand for quantities, and easy reflection on the surface. Common manual detection methods show problems of low efficiency or accuracy, easy to fatigue, and many others. To solve these problems, this paper proposes a new detection method to identify surface defects of mosaic ceramic tiles and designs a detection system platform to achieve rapid detection. The experiment proves that the detection system has a detection rate of 93.99% for small defects on the surface of mosaic ceramic tiles, and the detection time of a single mosaic ceramic tile is less than 0.06 s. The detection method can quickly and accurately screen out high-quality, defect-free mosaic ceramic tiles, which can effectively improve the quality and artistic value of mosaic ceramic art creation.     

对大中型钢结构企业生产管理体系的研究分析

以某大型钢结构制造企业为例,通过对产量分布、质量控制、劳动效率等基本数据的分析,研判外协生产管理体系方面存在的问题,从组织形态、管理模式、职能管理等多个维度提出了可行性建议,可为同类型钢结构制造企业提供经验借鉴。     

Coverage optimization algorithm based on VF-CS in mobile sensor network

A random placement of large-scale sensor network in the outdoor environment often causes low coverage.An area coverage optimization algorithm of mobile sensor network (MSN) based on virtual force perturbation and Cuckoo search (VF-CS) was proposed.Firstly,the virtual force of the sensor nodes within the Thiessen polygon was analyzed based on the partitioning of Voronoi diagram of the monitoring area.Secondly,the force of polygon vertices and neighbor nodes was taken as the perturbation factor for updating the node’s location of the Cuckoo search (CS).Finally,the VF-CS guided the node to move so as to achieve the optimal coverage.The simulation results demonstrate that the proposed algorithm has higher coverage and shorter average moving distance of nodes than the Voronoi diagram based algorithms in literatures.     

光纤有线电视在乡村振兴中的作用

2018年初,我国提出“乡村振兴”战略,此战略目的是增强农村农业发展的新活力,从而加速推进其现代化进程。光纤有线电视因具有损耗小、传输距离远、频带宽、传输容量大、抗电磁干扰等实用优势,并在贯彻及落实着“社会效益优先,两个效益统一”的原则下在社会、经济及文化等方面助力着乡村的振兴。     

Thermodynamic assessment of the Ga–Se–Te system

In this study, the Ga–Te binary system was reassessed by means of the CALPHAD method using a modified lattice stability parameter for Te as well as experimental data for this binary system. The two-sublattice ionic solution model was applied for the liquid phase, and the intermediate phases were described by the sublattice model. A set of self-consistent thermodynamic parameters was optimized for all the phases in the Ga–Te binary system, which reproduced the phase diagram and the thermodynamic properties well. Using the reevaluated Ga–Te system, previously assessed Ga–Se system, and modified Se–Te system, a critical evaluation of the Ga–Se–Te ternary system was performed. The calculated vertical sections, isothermal sections, and liquidus projection agreed reasonably well with the experimental data. Immiscibility in the liquid phase was observed, and the origin of this behavior is discussed from a thermodynamic perspective.     

沁水盆地赵庄矿3号煤层地面煤层气抽采低产原因分析

在对沁水盆地赵庄矿煤层气开发地质、煤层气生产井资料深入研究的基础上，分析、总结了区内煤层气直井低产原因，并据此提出了区内地面抽采后续开发方向。研究认为:3号煤层气含量偏低、含气饱和度低、临储比低，致使排采阶段气含量可降幅度低，是其低产的宏观表征；3号煤储层不匹配孔级，较差连通性，即微、小孔为主，中孔次之，大孔不发育，微裂隙连通性差，致使扩散缓慢、影响储层改造和抽采效果，是其低产的微观表征；3号煤层远高于顶底板塑性及相近的水平应力，进一步造成改造缝长受限，泄流面积不足。因此，建议区内后续地面抽采方式应以增大泄流面积开发方式为主。     

Interleukin-1β Modulation of the Mechanobiology of Primary Human Pulmonary Fibroblasts: Potential Implications in Lung Repair

Pro-inflammatory cytokines like interleukin-1β (IL-1β) are upregulated during early responses to tissue damage and are expected to transiently compromise the mechanical microenvironment. Fibroblasts are key regulators of tissue mechanics in the lungs and other organs. However, the effects of IL-1β on fibroblast mechanics and functions remain unclear. Here we treated human pulmonary fibroblasts from control donors with IL-1β and used Atomic Force Microscopy to unveil that IL-1β significantly reduces the stiffness of fibroblasts concomitantly with a downregulation of filamentous actin (F-actin) and alpha-smooth muscle (α-SMA). Likewise, COL1A1 mRNA was reduced, whereas that of collagenases MMP1 and MMP2 were upregulated, favoring a reduction of type-I collagen. These mechanobiology changes were functionally associated with reduced proliferation and enhanced migration upon IL-1β stimulation, which could facilitate lung repair by drawing fibroblasts to sites of tissue damage. Our observations reveal that IL-1β may reduce local tissue rigidity by acting both intracellularly and extracellularly through the downregulation of fibroblast contractility and type I collagen deposition, respectively. These IL-1β-dependent mechanical effects may enhance lung repair further by locally increasing pulmonary tissue compliance to preserve normal lung distension and function. Moreover, our results support that IL-1β provides innate anti-fibrotic protection that may be relevant during the early stages of lung repair.     

碱铝硅酸盐玻璃化学强化关键影响因素概述

化学强化是一种玻璃机械强度增强方法,适用于异型、超薄、高碱、高膨胀玻璃增强,因新型超薄显示产品的屏幕保护玻璃发展需要,化学强化技术重新在碱铝硅酸盐玻璃品种掀起研究热潮。本文对化学强化本质及铝硅酸盐玻璃在屏幕保护玻璃应用进行了回顾,基于玻璃化学强化的高CS、DOL和低CT诉求,归纳总结了关键影响因素,第1,碱铝硅酸盐玻璃的成分及结构是基础,氧化铝有利玻璃网络孔隙增大创造交换通道,氧化钠或氧化锂是离子交换关键物质;第2,对于玻璃组成和结构设计,要求玻璃网络键合度R=O/Si或O/(Si+Al)满足2.15~2.40,碱金属氧化物质量分数大于13%且膨胀系数大于6×10^-6/℃;第3,在化学强化工艺方面,化学强化温度决定离子扩散系数,化学强化时间决定DOL,一步法仅能获得相对较大的CS,而DOL不很理想,只有两种离子参与交换的二步法才有利于CS和DOL同步提高。     

Discovery of New Antiproliferative Imidazopyrazole Acylhydrazones Able To Interact with Microtubule Systems

Even though immunotherapy has radically changed the search for anticancer therapies, there are still many different pathways that are open to intervention with traditional small molecules. To expand our investigation in the anticancer field, we report here a new series of compounds in which our previous pyrazole and imidazopyrazole scaffolds are linked to a differently decorated phenyl ring through an acylhydrazone linker. Preliminary tests on the library were performed at the National Cancer Institute (USA) against the full NCI 60 cell panel. The best compounds among the imidazopyrazole series were then tested by immunofluorescence staining for their inhibition of cell proliferation, apoptosis induction, and their effect on the cell cycle and on microtubules. Two compounds, in particular 4-benzyloxy-3-methoxybenzyliden imidazopyrazole-7-carbohydrazide showed good growth inhibition, with IC₅₀ values in the low-micromolar range, and induced apoptosis. Both compounds altered the cell-cycle phases with the appearance of polyploid cells. Immunofluorescence analysis evidenced microtubules alterations; tubulin polymerization assays and docking studies suggested the tubulin system to be the possible, although not exclusive, target of the new acylhydrazone series reported here.